{
  "data": {
    "__count": 1,
    "__licence": {
      "identifier": "CC-BY-4.0",
      "link": "https://creativecommons.org/licenses/by/4.0",
      "name": "Creative Commons Attribution 4.0 International"
    },
    "results": {
      "Date": "2026-06-23 07:57:58",
      "DisorderGroup": "Group of disorders",
      "ORPHAcode": 685,
      "OrphanetURL": "http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=685",
      "Preferred term": "Hereditary spastic paraplegia",
      "Prevalence": [
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Europe",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "ORPHANET_2043954[PMID]_19339254[PMID]_19039240[PMID]_23609960[PMID]_1512613[PMID]",
          "ValMoy": "4.8"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Spain",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "2043954[PMID]_24603320[PMID]",
          "ValMoy": "9.6"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Portugal",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "23609960[PMID]_24603320[PMID]",
          "ValMoy": "4.1"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Sweden",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Not yet validated",
          "Source": "ORPHANET",
          "ValMoy": "1.3"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Libyan Arab Jamahiriya",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "4075075[PMID]_24603320[PMID]",
          "ValMoy": "2.1"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Worldwide",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "ORPHANET_24603320[PMID]",
          "ValMoy": "4.2"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Tunisia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "19438933[PMID]_24603320[PMID]",
          "ValMoy": "5.75"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Norway",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "19339254[PMID]_24603320[PMID]",
          "ValMoy": "7.4"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Italy",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "1512613[PMID]_3759416[PMID]_7793232[PMID]",
          "ValMoy": "2.7"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Estonia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "19039240[PMID]_24603320[PMID]",
          "ValMoy": "4.4"
        }
      ],
      "Typology": "Clinical group"
    }
  },
  "datasetCategory": {
    "lang": "en",
    "name": "Epidemiology of rare diseases"
  },
  "parameters": {
    "path": {
      "ORPHAcode": 685
    },
    "query": {}
  },
  "uri": "https://api.orphadata.com/rd-epidemiology/orphacodes/685"
}