{
  "data": {
    "__count": 1,
    "__licence": {
      "identifier": "CC-BY-4.0",
      "link": "https://creativecommons.org/licenses/by/4.0",
      "name": "Creative Commons Attribution 4.0 International"
    },
    "results": {
      "Date": "2026-06-23 07:57:58",
      "DisorderGroup": "Disorder",
      "ORPHAcode": 716,
      "OrphanetURL": "http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=716",
      "Preferred term": "Phenylketonuria",
      "Prevalence": [
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "France",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "11641035[PMID]_17616847[PMID]_[EXPERT]_Haute Autorit\u00c3\u00a9 de Sant\u00c3\u00a9 2010[OTHER]",
          "ValMoy": "6.0"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "France",
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          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "10.99"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Europe",
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          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "11.4"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Europe",
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          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "11.5079"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "United Kingdom",
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          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]_ORPHANET",
          "ValMoy": "3.4"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "United Kingdom",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "10.0"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Ireland",
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          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "22.0"
        },
        {
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          "PrevalenceGeographic": "Ireland",
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          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "22.0"
        },
        {
          "PrevalenceClass": "1-9 / 1 000 000",
          "PrevalenceGeographic": "Finland",
          "PrevalenceQualification": "Class only",
          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "8825928[PMID]_[EXPERT]",
          "ValMoy": "0.0"
        },
        {
          "PrevalenceClass": "1-9 / 1 000 000",
          "PrevalenceGeographic": "Finland",
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          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "0.8928"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "United States",
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          "ValMoy": "5.577"
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        {
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          "Source": "32668217[PMID]",
          "ValMoy": "4.0"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Latin America",
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          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "9.8"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
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          "ValMoy": "3.5999"
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        {
          "PrevalenceClass": "1-9 / 100 000",
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          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "5.5"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Brazil",
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          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "4.0"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Australia",
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          "ValMoy": "2.266"
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        {
          "PrevalenceClass": "1-9 / 100 000",
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          "ValMoy": "8.89"
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        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Iceland",
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          "PrevalenceValidationStatus": "Validated",
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        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Iceland",
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          "Source": "32668217[PMID]",
          "ValMoy": "11.9"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Japan",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Prevalence at birth",
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          "Source": "6468444[PMID]_20971365[PMID]_ ORPHANET",
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        {
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        {
          "PrevalenceClass": "1-9 / 100 000",
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          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "4.412"
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        {
          "PrevalenceClass": "1-9 / 100 000",
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          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "6.2798"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Thailand",
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        {
          "PrevalenceClass": "1-9 / 1 000 000",
          "PrevalenceGeographic": "Thailand",
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          "ValMoy": "0.4399"
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        {
          "PrevalenceClass": "1-9 / 100 000",
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          "ValMoy": "9.95"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Turkey",
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          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "14.99"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "United Arab Emirates",
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          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]",
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        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "United Arab Emirates",
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          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "6.89"
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        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Jordan",
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          "PrevalenceType": "Point prevalence",
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          "ValMoy": "20.0"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Jordan",
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          "PrevalenceType": "Prevalence at birth",
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          "Source": "10.1007/978-3-642-05080-0_11[DOI]",
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "India",
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Korea, Republic of",
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          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "2.439"
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        {
          "PrevalenceClass": "1-9 / 1 000 000",
          "PrevalenceGeographic": "Philippines",
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Singapore",
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          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "1.2"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Taiwan, Province of China",
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          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "1.6999"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Bahrain",
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          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "4.5"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Iran, Islamic Republic of",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "20.0"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Iraq",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "6.9998"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Slovakia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]",
          "ValMoy": "16.9"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Spain",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]",
          "ValMoy": "6.6"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Chile",
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          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]_ORPHANET",
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        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Iran, Islamic Republic of",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]_ORPHANET",
          "ValMoy": "7.271"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Canada",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]_ORPHANET",
          "ValMoy": "5.5"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Korea, Republic of",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]",
          "ValMoy": "5.1"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Taiwan, Province of China",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]_ORPHANET",
          "ValMoy": "1.433"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Worldwide",
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          "PrevalenceType": "Prevalence at birth",
          "PrevalenceValidationStatus": "Validated",
          "Source": "34082800[PMID]",
          "ValMoy": "6.4"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Israel",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "15.603"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Egypt",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "20.0"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Tunisia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "13.0005"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Austria",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "17.349"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Belarus",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "13.0005"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Bosnia and Herzegovina",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "10.0"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Bulgaria",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "3.746"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Croatia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "12.0004"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Cyprus",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "7.6923"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Czech Republic",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "19.1534"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Denmark",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "7.4437"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Estonia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "13.9997"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Germany",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "18.6567"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Greece",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "9.5969"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Hungary",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "11.1111"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Italy",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "25.0"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Latvia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "12.2399"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Lithuania",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "10.7526"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Moldova, Republic of",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "13.5998"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Netherlands",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "8.661"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Norway",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "8.7282"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Poland",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "12.3051"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Portugal",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "8.0"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Romania",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "10.0"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Russian Federation",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "12.9634"
        },
        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Serbia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "8.13"
        },
        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Slovakia",
          "PrevalenceQualification": "Value and class",
          "PrevalenceType": "Point prevalence",
          "PrevalenceValidationStatus": "Validated",
          "Source": "32668217[PMID]",
          "ValMoy": "17.3822"
        },
        {
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          "PrevalenceGeographic": "Sweden",
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          "PrevalenceClass": "1-9 / 100 000",
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          "PrevalenceGeographic": "New Caledonia",
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        {
          "PrevalenceClass": "1-9 / 100 000",
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        {
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Costa rica",
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Mexico",
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          "PrevalenceClass": "1-9 / 100 000",
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          "PrevalenceGeographic": "Austria",
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          "PrevalenceClass": "1-9 / 100 000",
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          "PrevalenceGeographic": "North Macedonia",
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Poland",
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          "ValMoy": "7.85"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Portugal",
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          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "6.0"
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        {
          "PrevalenceClass": "1-9 / 100 000",
          "PrevalenceGeographic": "Saudi Arabia",
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          "PrevalenceValidationStatus": "Validated",
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          "ValMoy": "7.02"
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        {
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          "PrevalenceGeographic": "India",
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          "Source": "32668217[PMID]_ORPHANET",
          "ValMoy": "13.34"
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        {
          "PrevalenceClass": "1-5 / 10 000",
          "PrevalenceGeographic": "Pakistan",
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          "Source": "32668217[PMID]",
          "ValMoy": "22.7"
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      ],
      "Typology": "Disease"
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  },
  "datasetCategory": {
    "lang": "en",
    "name": "Epidemiology of rare diseases"
  },
  "parameters": {
    "path": {
      "ORPHAcode": 716
    },
    "query": {}
  },
  "uri": "https://api.orphadata.com/rd-epidemiology/orphacodes/716"
}